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Finjan, founded in 1996, is a diversified technology company. Finjan's engineers and developers pioneered behavior-based, real-time detection of online threats, and the company's patents cover core functionality and features used in modern security architectures. Finjan operates four distinct business units:
An IP licensing business leverages a host of patents through its subsidiaries Finjan, Inc, Finjan Mobile and Finjan Blue.
The VitalSecurity™ platform protects consumer mobile devices in the workplace while securing personal and corporate data.
CyberRisk™ Security Solutions Ltd. provides bespoke risk assessment and cyber security consulting services to satisfy corporations’ compliance and governance needs.
Finjan also incubates up-and-coming technology startups pioneering a new generation of security technologies through its investment in Jerusalem Venture Partners (JVP) innovation funds.
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Fate Therapeutics (NASDAQ: FATE) is developing clinical-stage cellular immunotherapies for cancer and immune disorders, with an opportunity in 2018 to broadly establish the leading NK (natural killer) cell clinical franchise. The Company’s programs include:
- A first-in-class adaptive memory NK cell product candidate (FATE-NK100) designed to enhance direct tumor cell killing, resist immune checkpoints and promote endogenous T-cell anti-tumor response.
- Investigational New Drug (IND) cleared by FDA for initiation of clinical investigation in acute myelogenous leukemia (AML)
- A next-generation mobilized peripheral blood graft (ProTmune) for the prevention of graft-versus-host disease (GvHD) in patients with hematologic malignancies undergoing transplant
- Phase 1/2 PROTECT study ongoing
- ProTmune granted FDA Fast Track and Orphan Drug designations
- A human induced pluripotent stem cell (iPSC) platform that enables the generation of master cell lines to renewably create off-the-shelf engineered NK- and T-cell cancer immunotherapies
- Collaborations with University of Minnesota and Memorial Sloan Kettering for product candidate development
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Bio-Path Holdings (NASDAQ: BPTH) is a clinical stage biotechnology company developing therapeutics for the treatment of cancer and systemic diseases. Bio-Path's RNAi technology for drug development, DNAbilize™, uses a novel liposomal antisense DNA platform that allows for systemic delivery of nucleic acids without toxicity. Using DNAbilize™ clinicians can inhibit the production of proteins involved in cancer and block pathways involved in disease progression.
COMPANY HIGHLIGHTS
- Proprietary antisense and liposome delivery technology breakthrough for DNA drugs, potentially solving the challenges of delivering these molecules directly to target cells without side effects
- Original technology licensed from The MD Anderson Cancer Center. Company maintains strong relationship with the Cancer Center
- Strong IP position with composition of matter and method patents for antisense targets and manufacturing
- Lead product candidate, prexigebersen (Liposomal Grb2) formerly BP1001, in the clinic for blood cancers and in development for solid tumors. Second product candidate, BP1002 (Liposomal Bcl2) is IND-ready
- Promising clinical data for BP1001 shows that the drug has been well tolerated with possible anti-leukemic effects, including patients stabilizing for extended treatment
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