Fate Therapeutics (NASDAQ: FATE) is developing clinical-stage cellular immunotherapies for cancer and immune disorders, with an opportunity in 2018 to broadly establish the leading NK (natural killer) cell clinical franchise. The Company’s programs include:
A first-in-class adaptive memory NK cell product candidate (FATE-NK100) designed to enhance direct tumor cell killing, resist immune checkpoints and promote endogenous T-cell anti-tumor response.
Investigational New Drug (IND) cleared by FDA for initiation of clinical investigation in acute myelogenous leukemia (AML)
A next-generation mobilized peripheral blood graft (ProTmune) for the prevention of graft-versus-host disease (GvHD) in patients with hematologic malignancies undergoing transplant
Phase 1/2 PROTECT study ongoing
ProTmune granted FDA Fast Track and Orphan Drug designations
A human induced pluripotent stem cell (iPSC) platform that enables the generation of master cell lines to renewably create off-the-shelf engineered NK- and T-cell cancer immunotherapies
Collaborations with University of Minnesota and Memorial Sloan Kettering for product candidate development